Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 1 / Fall Semester | ||||
| Level of Course | 2nd Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | CHEMISTRY (MASTER'S DEGREE) | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | BAHAR TUBA FINDIK (btfindik@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | BAHAR TUBA FINDIK, | ||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The learning objective of the course is to introduce students to theoretical and practical aspects of enzymology by teaching the fundamental principles of enzyme structure, function, enzyme kinetic theories, enzyme catalysis mechanisms, enzyme regulation mechanisms in the cell, purification, immobilization, and industrial applications. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | can describe the structure and function of enzymes and the principles of enzyme catalysis. |
PO-1 Upon successful completion of this programme, graduate students will: Have advance knowledge and skills in the area of specialized.
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Examination Presentation |
| LO-2 | can describe the effect of enzyme structure on catalytic activities. |
PO-1 Upon successful completion of this programme, graduate students will: Have advance knowledge and skills in the area of specialized.
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Examination Presentation |
| LO-3 | can relate molecular structure to the biological activity |
PO-3 Evaluate the scientific data obtained from advance studies and present scientific results. |
Examination Presentation |
| LO-4 | can define the concepts of enzyme kinetics, related equations and estimate important parameters (Km. Vmax, Kcat, etc.) using these equations. |
PO-3 Evaluate the scientific data obtained from advance studies and present scientific results. |
Examination Presentation |
| LO-5 | can explain the basic concepts of purification, processing, and characterization of proteins. |
PO-1 Upon successful completion of this programme, graduate students will: Have advance knowledge and skills in the area of specialized.
PO-4 Defend the thesis that in the front of a jury composed by experts. |
Examination Presentation |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Fundamental principles of enzymology, chemical structure of enzymes, mechanism of enzyme catalyzed reactions, determination of active site, classification of enzymes , isolation and purification of enzyme, immobilized enzymes, industrial application of enzymes, enzyme in therapy and drug design, uses of enzymes in organic synthesis. | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Fundamental Principles of Enzymology, | Lecture, question and answer, discussion |
| 2 | Chemical Structure of Enzymes | Lecture, question and answer, discussion |
| 3 | Mechanism of Enzyme Catalyzed Reactions | Lecture, question and answer, discussion |
| 4 | Mechanism of Enzyme Catalyzed Reactions ( continues) | Lecture, question and answer, discussion |
| 5 | Enzyme Kinetics | Lecture, question and answer, discussion |
| 6 | Graphical Determination of Kinetic Constants | Lecture, question and answer, discussion |
| 7 | Enzyme İnhibition | Lecture, question and answer, discussion |
| 8 | mid-term exam | |
| 9 | Regulation of Enzyme Activity | Lecture, question and answer, discussion |
| 10 | Purification of Enzyme-I | Lecture, question and answer, discussion |
| 11 | Purification of Enzyme-II | Lecture, question and answer, discussion |
| 12 | Enzyme Activity and Activity Determination | Lecture, question and answer, discussion |
| 13 | Enzyme İmmobilization | Lecture, question and answer, discussion |
| 14 | İndustrial Enzymes | Lecture, question and answer, discussion |
| 15 | Artificial Enzyme | Lecture, question and answer, discussion |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Nelson DL, Cox MM, Lehninger. Biyokimyanın İlkeleri Kılıç N (Çeviri Editörü). 3. Baskı. Ankara: Palme yayıncılık; 2005.363- 408. | |
| 2 | Bisswanger, H., Enzyme Kinetics: Principles and Methods Wiley-VCH (May 13, 2002), ISBN 9783527806461. OCLC 992976641. | |
| Required Course instruments and materials | ||
| Projector | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 4 | ||
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | 8 | 40 | |
| 9.Project | |||
| final exam | 16 | 60 | |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 3 | 18 | 54 |
| b) Search in internet/Library | 2 | 18 | 36 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 0 | ||
| e) Term paper/Project | 4 | 8 | 32 |
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 0 | ||
| mid-term exam | 0 | ||
| Own study for final exam | 7 | 2 | 14 |
| final exam | 2 | 1 | 2 |
| 0 | |||
| 0 | |||
| Total work load; | 180 | ||