Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 4 / Fall Semester | ||||
| Level of Course | 1st Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ZÜBEYDE KUMBIÇAK (zkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The point of this lecture is to teach cell signal transduction mechanisms, several signal molecules including this mechanism and signal transduction pathway of this molecules. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | Can explain the cell signaling mechanisms. |
PO-1 Obtain basic knowledge of Biology PO-2 Develop an understanding of matter and energy in organisms PO-3 Identify structure-function relationships in cells and organisms PO-4 Define the relationship among life forms and their environments and ecosystems |
Examination |
| LO-2 | Can explain the cell signal molecules binding cell surface receptors. |
PO-3 Identify structure-function relationships in cells and organisms PO-8 Develop an awareness of continuous learning in relation with modern technology PO-9 Find out new methods to improve his/her knowledge PO-10 Demonstrate sufficiency in English to follow literature, present technical projects and write articles |
Examination |
| LO-3 | Can known the cAMP and cGMP pathways. |
PO-2 Develop an understanding of matter and energy in organisms PO-3 Identify structure-function relationships in cells and organisms PO-6 Develop an understanding of nature and history of scientific thought PO-7 Work effectively in multi-disciplinary research teams |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Cell signal transduction mechanisms and effect mechanisms of signal molecules, Cell signal molecules binding cell surface receptors, G Protein Coupled Receptors and Their Effectors, MAPK, JNK and p38 signal transduction pathways, NF-kB transcription factors. | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Introduction to cell signal transduction mechanisms | Explaining method |
| 2 | Signal transduction molecules and receptors | Explaining method |
| 3 | Cell-cell signal transduction types | Explaining method |
| 4 | Steroid hormones and nuclear receptor superfamily | Explaining method |
| 5 | Neural transmitters (neurotransmitters) Peptide hormones and growth factors | Explaining method |
| 6 | Ecosanoids Plant hormones | Explaining method |
| 7 | Functions of cell surface receptors G Protein-Associated Receptors | Explaining method |
| 8 | mid-term exam | |
| 9 | Receptor protein-tyrosine kinases | Explaining method |
| 10 | Cytokine receptors and non-receptor protein-tyrosine kinases | Explaining method |
| 11 | Intracellular signal transduction pathways Ras, Raf and MAP Kinase Pathway | Explaining method |
| 12 | Jak stat signaling pathway | Explaining method |
| 13 | Notch signaling pathway | Explaining method |
| 14 | Hedgehog signaling pathway | Explaining method |
| 15 | Other signal transduction pathways | Explaining method |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Cantley, L.C., Hunter, T., Sever, R., Thorner, J. 2014. “Signal Transduction, Principles, Pathways and Processes” | |
| Required Course instruments and materials | ||
| Ders notu | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 2 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 2 | 14 | 28 |
| Outside Class | |||
| a) Reading | 2 | 6 | 12 |
| b) Search in internet/Library | 3 | 6 | 18 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 2 | 5 | 10 |
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 2 | 5 | 10 |
| mid-term exam | 1 | 1 | 1 |
| Own study for final exam | 2 | 5 | 10 |
| final exam | 1 | 1 | 1 |
| 0 | |||
| 0 | |||
| Total work load; | 90 | ||