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| Year/Semester of Study | 3 / Spring Semester | ||||
| Level of Course | 1st Cycle Degree Programme | ||||
| Type of Course | Compulsory | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| Aim of the lecture is to explicate genome structure, epigenetic mechanisms, mechanisms of molecular genetic, transcription, translation, post-transcriptional and post-translational regulation mechanisms. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | Can explain the basic mechanisms of gene expression and protein synthesis, recombination and DNA repair mechanisms. |
PO-5 Explain transmission of genetic background in organisms and populations PO-8 Develop an awareness of continuous learning in relation with modern technology PO-9 Find out new methods to improve his/her knowledge PO-10 Demonstrate sufficiency in English to follow literature, present technical projects and write articles PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics PO-16 Explain the scientific findings clearly and efficiently both in written and verbal communications. |
Examination |
| LO-2 | Can explain the control mechanisms of gene expression. |
PO-3 Identify structure-function relationships in cells and organisms PO-5 Explain transmission of genetic background in organisms and populations PO-9 Find out new methods to improve his/her knowledge PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
| LO-3 | Can known the post-transcriptional and post-translational modifications. |
PO-7 Work effectively in multi-disciplinary research teams PO-8 Develop an awareness of continuous learning in relation with modern technology PO-9 Find out new methods to improve his/her knowledge PO-12 Demonstrate professional and ethical responsibility PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Genome structure, Replication epigenetic mechanisms, mechanisms of molecular genetic, transcription, translation, post-transcriptional and post-translational regulation mechanisms | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | History of molecular genetics and the discovery of nucleic acids | Explanation |
| 2 | Structure of DNA and organization of DNA in chromosomes | Explanation |
| 3 | The order of genes in the genome and changes in the order of the genes | Explanation |
| 4 | DNA replication | Explanation |
| 5 | Structure and types of RNA | Explanation |
| 6 | Transcription | Explanation |
| 7 | Post-transcriptional modifications | Explanation |
| 8 | mid-term exam | |
| 9 | Translation and proteins | Explanation |
| 10 | Post-translational modifications | Explanation |
| 11 | Regulation of gene expression in prokaryotes | Explanation |
| 12 | Regulation of gene expression in eukaryotes | Explanation |
| 13 | Molecular genetics of bacteria and viruses | Explanation |
| 14 | Extrachromosomal DNA in eukaryotes | Explanation |
| 15 | Mutations and DNA repair mechanisms | Explanation |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Leland Hartwell, Leroy Hood, Michael Goldberg, Ann Reynolds and Lee Silver, 2011. Genetics: From Gene to Genomes 4. basım, McGraw-Hill Science/Engineering/Math. | |
| 2 | Strachan and Read. Human Molecular Genetics 4 Wiley. 2011 | |
| 3 | Güler Temizkan Moleküler Genetik | |
| 4 | Mehmet Topaktaş Moleküler Genetik | |
| Required Course instruments and materials | ||
| textbook, course presentations | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 2 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 2 | 14 | 28 |
| b) Search in internet/Library | 1 | 14 | 14 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 0 | ||
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 2 | 8 | 16 |
| mid-term exam | 2 | 1 | 2 |
| Own study for final exam | 2 | 8 | 16 |
| final exam | 2 | 1 | 2 |
| 0 | |||
| 0 | |||
| Total work load; | 120 | ||