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| Year/Semester of Study | 4 / Fall Semester | ||||
| Level of Course | 1st Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The aim of this lecture is to teach basic molecular mechanisms about genesis and development of cancer. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | Can explain the DNA repair mechanism. |
PO-3 Identify structure-function relationships in cells and organisms PO-6 Develop an understanding of nature and history of scientific thought PO-8 Develop an awareness of continuous learning in relation with modern technology PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
| LO-2 | Can known tumor suppressor genes. |
PO-1 Obtain basic knowledge of Biology PO-2 Develop an understanding of matter and energy in organisms PO-3 Identify structure-function relationships in cells and organisms PO-9 Find out new methods to improve his/her knowledge PO-12 Demonstrate professional and ethical responsibility |
Examination |
| LO-3 | Can known the apoptosis. |
PO-2 Develop an understanding of matter and energy in organisms PO-3 Identify structure-function relationships in cells and organisms PO-6 Develop an understanding of nature and history of scientific thought PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Mechanism of cancer, Causes of cancer, DNA repair systems, Tumor suppressor genes, Apoptosis, Onkogenes, Tumor viruses, Molecular therapeutic strategies in cancer | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Definition and mechanism of Cancer | Explaining |
| 2 | Carcinogenic agents and cancer stages | Explaining |
| 3 | Mutations and their role in the cancer process | Explaining |
| 4 | DNA repair mechanisms and cancer | Explaining |
| 5 | Tumor suppressor genes | Explaining |
| 6 | Protooncogenes and oncogenes | Explaining |
| 7 | Telomerase activity and tumor viruses in cancer cells | Explaining |
| 8 | mid-term exam | |
| 9 | Cell cycle and cancer | Explaining |
| 10 | Apoptosis mechanism and its role in cancer | Explaining |
| 11 | Epigenetic mechanisms in cancer | Explaining |
| 12 | Growth factors and receptors | Explaining |
| 13 | Intracellular signal transduction mechanisms and cancer pathways | Explaining |
| 14 | Multistep carcinogenesis and metastasis biology | Explaining |
| 15 | Diagnosis and therapy in Cancer | Explaining |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Molecular Biology of Cancer Mechanisms, Targets and Therapeutics, Lauren Pecorino | |
| Required Course instruments and materials | ||
| Slides about this lecture subjects | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 2 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 2 | 14 | 28 |
| Outside Class | |||
| a) Reading | 2 | 6 | 12 |
| b) Search in internet/Library | 3 | 6 | 18 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 2 | 5 | 10 |
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 2 | 5 | 10 |
| mid-term exam | 1 | 1 | 1 |
| Own study for final exam | 2 | 5 | 10 |
| final exam | 1 | 1 | 1 |
| 0 | |||
| 0 | |||
| Total work load; | 90 | ||