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| Year/Semester of Study | 4 / Fall Semester | ||||
| Level of Course | 1st Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| To have knowledge about mutations and mutagens and to explain the mechanisms of cancerogens. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | Can explain the mutation and mutagens. |
PO-8 Develop an awareness of continuous learning in relation with modern technology PO-9 Find out new methods to improve his/her knowledge PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
| LO-2 | Can known the gene and genom mutations. |
PO-9 Find out new methods to improve his/her knowledge PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
| LO-3 | Can explain the techniques used in the detection of mutations. |
PO-9 Find out new methods to improve his/her knowledge PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Chromosomes, genes and genome mutations, spontaneous and induced mutations, and mechanisms of physical and chemical mutagens, carcinogens . | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Introduction to toxicology | Explaining, Question and answer teaching method |
| 2 | Classification of poisons | Explaining, Question and answer teaching method |
| 3 | Important toxic substances found in our environment and industry: Pesticides, Insecticides, fumigants and insect repellants | Explaining, Question and answer teaching method |
| 4 | Important toxic substances found in our environment and industry: Herbicides, rodenticides, Fungicides, airborn poisons and other sources of toxicity | Explaining, Question and answer teaching method |
| 5 | Ways of entry of poisons into the body, absorption, distribution and excretion ways | Explaining, Question and answer teaching method |
| 6 | Metabolism of toxic substances | Explaining, Question and answer teaching method |
| 7 | Mechanisms of action of toxic substances | Explaining, Question and answer teaching method |
| 8 | mid-term exam | |
| 9 | Effects of toxic substances on organs and systems in our body | Explaining, Question and answer teaching method |
| 10 | Genetic toxicity and changes in cells after exposure to genotoxic substances | Explaining, Question and answer teaching method |
| 11 | Mutations and factors causing mutations | Explaining, Question and answer teaching method |
| 12 | Genotoxic Carcinogens | Explaining, Question and answer teaching method |
| 13 | Teratogens | Explaining, Question and answer teaching method |
| 14 | Investigation of genotoxicity and risk analysis | Explaining, Question and answer teaching method |
| 15 | Genotoxicological test methods | Explaining, Question and answer teaching method |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Molecular Biology of the Cell, Alberts, Garland Science | |
| 2 | Molecular Cell Biology, Lodish, WH Freeman and Company. | |
| Required Course instruments and materials | ||
| Text Book | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 2 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 2 | 14 | 28 |
| Outside Class | |||
| a) Reading | 2 | 6 | 12 |
| b) Search in internet/Library | 3 | 6 | 18 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 2 | 5 | 10 |
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 2 | 5 | 10 |
| mid-term exam | 1 | 1 | 1 |
| Own study for final exam | 2 | 5 | 10 |
| final exam | 1 | 1 | 1 |
| 0 | |||
| 0 | |||
| Total work load; | 90 | ||