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Year/Semester of Study | 1 / Spring Semester | ||||
Level of Course | 3rd Cycle Degree Programme | ||||
Type of Course | Optional | ||||
Department | MOLECULAR BIOLOGY AND GENETICS (PHD) | ||||
Pre-requisities and Co-requisites | None | ||||
Mode of Delivery | Face to Face | ||||
Teaching Period | 14 Weeks | ||||
Name of Lecturer | NAŞİT İĞCİ (nasitigci@nevsehir.edu.tr) | ||||
Name of Lecturer(s) | |||||
Language of Instruction | Turkish | ||||
Work Placement(s) | None | ||||
Objectives of the Course | |||||
The aim of this course is to give information about protein biochemistry, protein purification methods, protein engineering, antibody production and to give examples of how proteins can be used as biotechnological products. |
Learning Outcomes | PO | MME | |
The students who succeeded in this course: | |||
LO-1 | can explain the basic concepts of biotechnology. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology |
Examination |
LO-2 | can explain how proteins are used as biotechnological products. |
PO-1 Have information about current issues in molecular biology and genetics. |
Examination |
LO-3 | can conduct research on the commercial value of biotechnological products. |
PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
LO-4 | can explain how proteins are produced to be used as biotechnological products. |
PO-1 Have information about current issues in molecular biology and genetics. PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own |
Examination |
PO: Programme Outcomes MME:Method of measurement & Evaluation |
Course Contents | ||
Protein biochemistry, protein separation and purification methods, protein engineering, antibodies as a biotechnological product, antibody production and engineering, large-scale production of proteins, enzymes as a biotechnological product, enzyme immobilization, recombinant DNA technology. | ||
Weekly Course Content | ||
Week | Subject | Learning Activities and Teaching Methods |
1 | Definition and history of biotechnology. | Lecture notes, books, related articles, computer |
2 | Protein biochemistry | Lecture notes, books, related articles, computer |
3 | Uses of proteins as a biotechnological product | Lecture notes, books, related articles, computer |
4 | Antibodies as a biotechnological product | Lecture notes, books, related articles, computer |
5 | Antibody development | Lecture notes, books, related articles, computer |
6 | Pilot and large-scale production of antibodies | Lecture notes, books, related articles, computer |
7 | Uses of antibody drugs | Lecture notes, books, related articles, computer |
8 | mid-term exam | |
9 | Enzymes and other proteins as biotechnological products | Lecture notes, books, related articles, computer |
10 | Enzyme immobilization and usage areas of enzymes | Lecture notes, books, related articles, computer |
11 | Industrial production of enzymes | Lecture notes, books, related articles, computer |
12 | The use of recombinant DNA technology in protein production. | Lecture notes, books, related articles, computer |
13 | Use of bioreactors in protein production. | Lecture notes, books, related articles, computer |
14 | Biosafety in the production of proteins as biotechnological products. | Lecture notes, books, related articles, computer |
15 | Biotechnology companies and bioentrepreneurship. | Lecture notes, books, related articles, computer |
16 | final exam | |
Recommend Course Book / Supplementary Book/Reading | ||
1 | Thieman & Palladino. 2013. Biyoteknolojiye Giriş. Palme Yayınları. | |
2 | Walsh G. (2001). Proteins: Biochemistry and Biotechnology. Wiley. | |
Required Course instruments and materials | ||
Lecture notes, books, related articles, computer |
Assessment Methods | |||
Type of Assessment | Week | Hours | Weight(%) |
mid-term exam | 8 | 40 | |
Other assessment methods | |||
1.Oral Examination | |||
2.Quiz | |||
3.Laboratory exam | |||
4.Presentation | |||
5.Report | |||
6.Workshop | |||
7.Performance Project | |||
8.Term Paper | |||
9.Project | |||
final exam | 16 | 60 |
Student Work Load | |||
Type of Work | Weekly Hours | Number of Weeks | Work Load |
Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
Outside Class | |||
a) Reading | 3 | 14 | 42 |
b) Search in internet/Library | 3 | 14 | 42 |
c) Performance Project | 0 | ||
d) Prepare a workshop/Presentation/Report | 0 | ||
e) Term paper/Project | 0 | ||
Oral Examination | 0 | ||
Quiz | 0 | ||
Laboratory exam | 0 | ||
Own study for mid-term exam | 3 | 7 | 21 |
mid-term exam | 2 | 1 | 2 |
Own study for final exam | 3 | 7 | 21 |
final exam | 2 | 1 | 2 |
0 | |||
0 | |||
Total work load; | 172 |