Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 1 / Spring Semester | ||||
| Level of Course | 2nd Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | BİYOLOJİ(DOKTORA) | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | AYSEL KEKİLLİOĞLU (akekillioglu@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The aim of this course is to give information about the modern bioanalytical methods used in the investigation of animal venoms and to explain the strategies followed in experimental studies by using these techniques. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | can give information about the biochemistry of animal venoms. |
PO-1 Have an advanced level of knowledge about the recent and best practices in Biology, deepen and expand their knowledge on the expert level, conduct and assess the analyses by employing statistical methods PO-2 Plan experiments and carry out original researches in the field by making use of the theoretical and practical knowledge at the expert level that they have obtained in their field PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Have the qualification and capability to gain admission to doctoral programs, R&D units or occupations related to the field with the knowledge they have gathered in the field PO-10 Monitor and supervise the social, scientific, cultural and ethical values in the process of collecting, interpreting, implementing and publishing the data related to the field of Biology and teach those values |
Examination Performance Project |
| LO-2 | can give information about the modern bioanalytical methods used in the investigation of animal venoms. |
PO-1 Have an advanced level of knowledge about the recent and best practices in Biology, deepen and expand their knowledge on the expert level, conduct and assess the analyses by employing statistical methods PO-2 Plan experiments and carry out original researches in the field by making use of the theoretical and practical knowledge at the expert level that they have obtained in their field PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Have the qualification and capability to gain admission to doctoral programs, R&D units or occupations related to the field with the knowledge they have gathered in the field PO-10 Monitor and supervise the social, scientific, cultural and ethical values in the process of collecting, interpreting, implementing and publishing the data related to the field of Biology and teach those values |
Examination Performance Project |
| LO-3 | can explain the aims and approaches of modern bioanalytical methods for the investigation of animal venoms. |
PO-1 Have an advanced level of knowledge about the recent and best practices in Biology, deepen and expand their knowledge on the expert level, conduct and assess the analyses by employing statistical methods PO-2 Plan experiments and carry out original researches in the field by making use of the theoretical and practical knowledge at the expert level that they have obtained in their field PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Have the qualification and capability to gain admission to doctoral programs, R&D units or occupations related to the field with the knowledge they have gathered in the field PO-10 Monitor and supervise the social, scientific, cultural and ethical values in the process of collecting, interpreting, implementing and publishing the data related to the field of Biology and teach those values |
Examination Performance Project |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| The general features and biochemistry of venom in vertebrate and invertebrate animals, methods of extracting and storing venoms, electrophoretic, chromatographic, spectrometric and spectroscopic methods used for investigating animal venoms, a new peptide/protein identification process from animal venoms, peptide synthesis and recombinant production of animal venom proteins, standardization in animal venom studies | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Biochemistry of invertebrate venoms. | Lecture, Discussion, Question Answer, Literature Search |
| 2 | Biochemistry of vertebrate venoms. | Lecture, Discussion, Question Answer, Literature Search |
| 3 | Methods of extracting venom from invertebrate and vertebrate animals. | Lecture, Discussion, Question Answer, Literature Search |
| 4 | The methods used in storing the venom and preparation of the venom samples for the studies. | Lecture, Discussion, Question Answer, Literature Search |
| 5 | Electrophoretic methods used in the investigation of animal venoms. | Lecture, Discussion, Question Answer, Literature Search |
| 6 | Chromatographic methods used in the investigation of animal venoms. | Lecture, Discussion, Question Answer, Literature Search |
| 7 | Mass spectrometry methods used in the investigation of animal venoms. | Lecture, Discussion, Question Answer, Literature Search |
| 8 | mid-term exam | |
| 9 | Spectroscopic methods used in the investigation of animal venoms. | Lecture, Discussion, Question Answer, Literature Search |
| 10 | Process of a new peptide/protein identification in animal venoms I: Purification. | Lecture, Discussion, Question Answer, Literature Search |
| 11 | Process of a new peptide/protein identification in animal venoms II: Determination of the amino acid sequence, identification of the gene when necessary, and family identification and function prediction by bioinformatic analysis. | Lecture, Discussion, Question Answer, Literature Search |
| 12 | Process of a new peptide/protein identification in animal venoms III: Determining biological/pharmacological activities. | Lecture, Discussion, Question Answer, Literature Search |
| 13 | Production of peptides/proteins purified from animal venoms by chemical synthesis and recombinant protein techniques. | Lecture, Discussion, Question Answer, Literature Search |
| 14 | The methods used to determine 3-dimensional structures of purified peptides and proteins. | Lecture, Discussion, Question Answer, Literature Search |
| 15 | Ensuring the reproducibility of bioanalytical methods used for investigating animal venoms. | Lecture, Discussion, Question Answer, Literature Search |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Radis-Baptista G (Ed). 2013. An Integrated View of the Molecular Recognition and Toxinology – From Analytical Procedures to Biomedical Applications. InTech. | |
| 2 | Edstrom A. 1992. Venomous and Poisonous Animals. Krieger Publishing Company, Florida. | |
| 3 | Menez A (Ed). 2002. Perspectives in Molecular Toxinology. Wiley. | |
| 4 | Mackessy SP (Ed). 2010. Handbook of Venoms and Toxins of Reptiles. CRC Press, Florida. | |
| Required Course instruments and materials | ||
| Lecture notes, books, related articles, computer | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 2 | 20 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | 15 | 1 | 40 |
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 3 | 40 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 3 | 14 | 42 |
| b) Search in internet/Library | 3 | 14 | 42 |
| c) Performance Project | 2 | 14 | 28 |
| d) Prepare a workshop/Presentation/Report | 0 | ||
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 1 | 7 | 7 |
| mid-term exam | 2 | 1 | 2 |
| Own study for final exam | 2 | 7 | 14 |
| final exam | 3 | 1 | 3 |
| 0 | |||
| 0 | |||
| Total work load; | 180 | ||