Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

INSTITUTE OF SCIENCE / KİM614 - TEKLİF EDİLEN KIMYA (DOKTORA)

Code: KİM614 Course Title: MEMBRANE BIOCHEMISTRY Theoretical+Practice: 3+0 ECTS: 6
Year/Semester of Study 1 / Spring Semester
Level of Course 3rd Cycle Degree Programme
Type of Course Optional
Department TEKLİF EDİLEN KIMYA (DOKTORA)
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer BAHAR TUBA FINDIK (btfindik@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this course is to introduce students to the basic concepts of cell membranes, their structures, and the chemical compositions responsible for their unique functions of biomembranes, with an emphasis on membrane transport. In addition, students are provided with an understanding of the concept of chemical thermodynamics and how it is applied in cells.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 Can comprehend and compare the chemical compositions and general properties of membranes. PO-1 Develop advanced theoretical and applied knowledge in the field, depending on undergraduate and graduate qualifications.
PO-2 Can make connections between different disciplines and sub-fields that their field is related to by using their expert knowledge and skills, work in harmony in research groups.
 		Examination
LO-2 Can comprehend the types, characteristics, and functions of membrane proteins and carbohydrates in the cell membrane. PO-1 Develop advanced theoretical and applied knowledge in the field, depending on undergraduate and graduate qualifications.
PO-4 Can systematically follow up-to-date information in the field.
PO-8 Can design theoretical, experimental, or modeling-based research that will contribute to progress in the field, develop new scientific methods, and apply a known method to a different field.
 		Examination
LO-3 Can make a presentation by combining the information learned in the course with current literature. PO-5 Can have the ability to search literature, make presentations, design and prepare experimental setups, and interpret the relevant results.
 		Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Introduction to biological membranes, basics of membrane structure, general properties and classification of lipids, lipid components and chemical properties of membranes, lipid composition of membranes, monolayer, bilayer, micelles, liposomes and biomembranes, protein components of membranes; structure, arrangement and properties, protein-lipid interactions and membrane function, membrane carbohydrates and functions, membrane transport, primary ion pumps and ionic gradient formation, structure and function of P-type ATPases, ABC-transporters, transporter transport, molecular mechanism, biological perspective to channel functions, ion channels, ion-carrying and channel-forming ionophores, signal transmission topics constitute the contents of this course.
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Introduction to biological membranes, basics of membrane structure Lecture, question and answer, discussion
2 General properties and classification of lipids Lecture, question and answer, discussion
3 Lipid compositions and chemical properties of membranes Lecture, question and answer, discussion
4 Lipid composition of membranes, monolayer, bilayer, micelles, liposomes and biomembranes Lecture, question and answer, discussion
5 Protein components of membranes; structure, arrangement and properties Lecture, question and answer, discussion
6 Protein-lipid interactions and membrane function Lecture, question and answer, discussion
7 Membrane carbohydrates and their functions Lecture, question and answer, discussion
8 mid-term exam
9 Membrane transport Lecture, question and answer, discussion
10 Primary ion pumps and ionic gradient formation, Structure and function of P-type ATPases, ABC-transporters Lecture, question and answer, discussion
11 Carrier transport, molecular mechanism Lecture, question and answer, discussion
12 Biological view of channel functions, ion channels, ion-carrying and channel-forming ionophores Lecture, question and answer, discussion
13 Signal transduction Lecture, question and answer, discussion
14 Student presentations Question and answer, discussion
15 Student presentations Question and answer, discussion
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Vance J.E. , Vance D.E. (2002). Lipid Biyokimyası, Lipoproteinler ve membranlar, Elsevier Science
Required Course instruments and materials
Lecture notes, books, related articles, computer

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 2 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation 14 ve 15 6 20
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 40

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 3 10 30
       b) Search in internet/Library 3 14 42
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 5 4 20
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 3 6 18
mid-term exam 2 1 2
Own study for final exam 4 6 24
final exam 2 1 2
0
0
Total work load; 180